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Invitrogen
NOD4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-21017
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
An 18 amino acid peptide near the amino terminus of human NOD4.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control is EL4 cell lysate.
PA5-21017 can be used with blocking peptide PEP-1131.
靶标信息
NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-kappa-B and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Protein NLRC5
基因别名: AI451557; AK220210; Nlrc5; NOD27
UniProt ID: (Mouse) C3VPR6
Entrez Gene ID: (Mouse) 434341
immune system process
negative regulation of NF-kappaB transcription factor activity
regulation of kinase activity
innate immune response
positive regulation of MHC class I biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of interferon-gamma-mediated signaling pathway
negative regulation of type I interferon-mediated signaling pathway
positive regulation of type I interferon-mediated signaling pathway
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
