Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • PCR Equipment and Supplies
    • Chromatography Columns and Cartridges
    • Lab Centrifuges
    • Molecular Biology Reagents and Kits
    • Lab Plasticware and Supplies
    • See all product categories
  • Applications
    • Chromatography
    • Cell Culture
    • Real-Time PCR
    • Mass Spectrometry
    • Lab Plasticware and Supplies
    • Electron Microscopy
    • Protein Biology
    • PCR
    • RNAi
    • Environmental
    • See all applications and techniques
  • Services
    • Custom Services
    • Enterprise-Level Lab Informatics
    • Financial and Leasing Services
    • Instrument Services
    • OEM and Commercial Supply
    • Training Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • Learning Centers
    • Contact Us
    • Change Location
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Who We Serve
    • Antibody Therapy Solution
    • Cell and Gene Therapy Solution
    • Academic
    • Industrial and Applied Sciences
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search

Search All
Search button
          • Contact Us
          • Quick Order
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • Membership
            • AR Statement & Invoice Inquiry
            • Custom Products & Projects
          • Primary Antibodies ›
          • Angiotensinogen Antibodies

          Invitrogen

          Angiotensinogen Polyclonal Antibody

          Advanced Verification
          1 Published Figure
          2 References
          View all (17) Angiotensinogen antibodies

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support

          Cite Angiotensinogen Polyclonal Antibody

          Additional Information:

          {{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
          • Antibody Testing Data (8)
          • Published Figures (1)
          • Advanced Verification (1)
          Angiotensinogen Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Angiotensinogen Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

          {{ $ctrl.currentElement.advancedVerification.fullName }}
          {{ $ctrl.currentElement.advancedVerification.text }}

          Angiotensinogen Antibody (PA5-21520) in ICC/IF

          Immunofluorescence analysis of Angiotensinogen was performed using 70% confluent log phase Hep G2 cells treated with 1X protein transport inhibitor (Product # 00-4980-03) for 4 hours. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. cells were labeled with Angiotensinogen Polyclonal Ant... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

          {{$ctrl.videoDesc}}

          {{$ctrl.videoLongDesc}}

          Angiotensinogen Antibody in Immunocytochemistry (ICC/IF)
          Angiotensinogen Antibody in Immunocytochemistry (ICC/IF)
          Angiotensinogen Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Angiotensinogen Antibody in Western Blot (WB)
          Angiotensinogen Antibody in Western Blot (WB)
          Angiotensinogen Antibody in Western Blot (WB)
          Angiotensinogen Antibody in Western Blot (WB)
          Angiotensinogen Antibody in Western Blot (WB)
          Angiotensinogen Antibody in Immunocytochemistry (ICC/IF)
          Angiotensinogen Antibody

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          Product Details

          PA5-21520

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:1,000
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human Angiotensinogen. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 10% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_11153449

          Product Specific Information

          Recommended positive controls: HepG2, human plasma, mouse plasma, rat plasma.

          Predicted reactivity: Chimpanzee (99%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          The protein encoded by AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: alpha-1 antiproteinase, antitrypsin; angiotensin I; angiotensin II; angiotensin ll; angiotensinogen (serpin peptidase inhibitor, clade A, member 8); fetal-liver predominant transporter 1; pre-angiotensinogen; preangiotensinogen; serine (or cysteine) proteinase inhibitor; serpin A8; serpin peptidase inhibitor, clade A, member 8; unnamed protein product

          View more View less

          Gene Aliases: Ang; AngI; AngII; ANHU; ANRT; Aogen; hFLT1; PAT; SERPINA8

          View more View less

          UniProt ID: (Human) P01019, (Rat) P01015

          View more View less

          Entrez Gene ID: (Human) 183, (Rat) 24179, (Mouse) 11606

          View more View less

          Function(s)
          serine-type endopeptidase inhibitor activity hormone activity protein binding growth factor activity superoxide-generating NADPH oxidase activator activity sodium channel regulator activity type 1 angiotensin receptor binding type 2 angiotensin receptor binding receptor agonist activity
          Process(es)
          ovarian follicle rupture blood vessel development branching involved in ureteric bud morphogenesis positive regulation of cytokine production kidney development regulation of systemic arterial blood pressure by circulatory renin-angiotensin angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure renin-angiotensin regulation of aldosterone production regulation of renal output by angiotensin regulation of heart rate vasodilation by angiotensin involved in regulation of systemic arterial blood pressure regulation of blood vessel size by renin-angiotensin brain renin-angiotensin system renal system process angiotensin-mediated drinking behavior regulation of systemic arterial blood pressure by renin-angiotensin positive regulation of extracellular matrix constituent secretion protein import into nucleus cellular sodium ion homeostasis cell-matrix adhesion cell surface receptor signaling pathway G-protein coupled receptor signaling pathway adenylate cyclase-activating G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration female pregnancy establishment of blood-nerve barrier regulation of blood pressure positive regulation of cell proliferation negative regulation of cell proliferation associative learning response to cold response to mechanical stimulus response to salt stress regulation of gene expression positive regulation of endothelial cell migration positive regulation of cardiac muscle hypertrophy positive regulation of gene expression negative regulation of gene expression positive regulation of cardiac muscle cell apoptotic process positive regulation of norepinephrine secretion positive regulation of epithelial to mesenchymal transition positive regulation of macrophage derived foam cell differentiation positive regulation of neuron projection development artery smooth muscle contraction response to muscle activity involved in regulation of muscle adaptation negative regulation of angiogenesis vasopressin secretion extracellular matrix organization negative regulation of cell growth peristalsis response to estradiol positive regulation of superoxide anion generation positive regulation of peptidyl-serine phosphorylation negative regulation of tissue remodeling operant conditioning positive regulation of insulin secretion involved in cellular response to glucose stimulus aldosterone secretion angiotensin-activated signaling pathway positive regulation of multicellular organism growth vasoconstriction vasodilation hormone metabolic process drinking behavior regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of MAP kinase activity positive regulation of MAPK cascade negative regulation of neuron apoptotic process positive regulation of nitric oxide biosynthetic process positive regulation of fatty acid biosynthetic process positive regulation of epidermal growth factor receptor signaling pathway positive regulation of blood pressure positive regulation of transcription, DNA-templated positive regulation of organ growth positive regulation of insulin receptor signaling pathway astrocyte activation fibroblast proliferation positive regulation of fibroblast proliferation regulation of long-term neuronal synaptic plasticity smooth muscle cell proliferation regulation of inflammatory response positive regulation of inflammatory response smooth muscle cell differentiation negative regulation of neurotrophin TRK receptor signaling pathway stress-activated MAPK cascade positive regulation of protein kinase B signaling regulation of calcium ion transport regulation of transmission of nerve impulse cell growth involved in cardiac muscle cell development ERK1 and ERK2 cascade uterine smooth muscle contraction cellular response to mechanical stimulus positive regulation of branching involved in ureteric bud morphogenesis positive regulation of cholesterol metabolic process positive regulation of protein kinase C activity regulation of extracellular matrix assembly positive regulation of extracellular matrix assembly positive regulation of membrane hyperpolarization positive regulation of pri-miRNA transcription from RNA polymerase II promoter positive regulation of gap junction assembly regulation of cardiac conduction cellular response to angiotensin positive regulation of vascular smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell migration positive regulation of L-lysine import across plasma membrane positive regulation of L-arginine import across plasma membrane response to angiotensin positive regulation of reactive oxygen species metabolic process positive regulation of extrinsic apoptotic signaling pathway regulation of cell growth blood vessel remodeling regulation of blood volume by renin-angiotensin G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger phospholipase C-activating G-protein coupled receptor signaling pathway cell-cell signaling regulation of vasoconstriction low-density lipoprotein particle remodeling regulation of renal sodium excretion nitric oxide-cGMP-mediated signaling pathway regulation of cell proliferation negative regulation of sodium ion transmembrane transport proteasome-mediated ubiquitin-dependent protein catabolic process renal sodium ion absorption positive regulation of angiotensin-activated signaling pathway
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us - 400 820 8982
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us About Us
          • Careers Careers
          • Investors Investors
          • News News
          • Social Responsibility Social Responsibility
          • Trademarks
          • Policies and Notices
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Policy
          • Price & Freight Policy
          © 2006-2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          China flag icon
          China
          本网站销售的所有产品均不得用于人类或动物之临床诊断或治疗,仅可用于工业或者科研等非医疗目的。
          经营证照公示 | ICP备案号:沪ICP备11003924号 | 沪公网安备 31011502006935号

          Your items have has been added!


          Host server : magellan-search-blue-74d7b4b4d9-p95z8:80/100.66.74.151:80.
          git-commit: 7aafa54bd143a040505a257d2a3ebda4095a617f
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.56.0-Offline