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Invitrogen
TRPM2 Polyclonal Antibody
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TRPM2 Antibody (PA5-22218) in IHC (P)
TRPM2 Polyclonal Antibody detects TRPM2 protein at cytoplasm in rat liver by immunohistochemical analysis. Sample: Paraffin-embedded rat liver. TRPM2 Polyclonal Antibody (Product # PA5-22218) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-22218
产品规格
种属反应
Human,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the Intracellular domain of human TRPM2. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.38 mg/mL
规格
138 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HepG2, HepG2 membrane extract.
Predicted reactivity: Mouse (90%), Rat (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
TRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: EC 3.6.1.13; EREG 1; KNP 3; LTRPC 2; MGC133383; null; Transient receptor potential cation channel subfamily M member 2; transient receptor potential melastatin family 2; TRPC 7; TRPM 2
基因别名: Trpm2; Trpm2-predicted
UniProt ID: (Rat) E9PTA2
Entrez Gene ID: (Rat) 294329
Disclaimer
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