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Invitrogen
DVL1 Polyclonal Antibody
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DVL1 Antibody (PA5-23409) in WB
Western blot analysis of DVL1 in Raji cell lysate in the 1) absence and 2) presence of immunizing peptide. Samples were incubated in DVL1 polyclonal antibody (Product # PA5-23409) followed by a goat anti-rabbit Ig HRP secondary antibody. PicoTect ECL substrate solution was used for this test.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-23409
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A portion of amino acids 70-120 of human DVL-1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cellproliferation, acting as a transducer molecule for developmentalprocesses, including segmentation and neuroblast specification.DVL1 is a candidate gene for neuroblastomatous transformation. TheSchwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2Ahave been mapped to the same region as DVL1. The phenotypes ofthese diseases may be consistent with defects which might beexpected from aberrant expression of a DVL gene during development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dishevelled 1; dishevelled 1 (homologous to Drosophila dsh); dishevelled, dsh homolog 1; Dishevelled-1; Dishevelled-1-like; DSH homolog 1; DSH homolog 1-like; MGC54245; RP5-890O3.5; Segment polarity protein dishevelled homolog DVL-1; unnamed protein product
基因别名: DRS2; DVL; dvl-1; DVL1; DVL1L1; mKIAA4029
UniProt ID: (Rat) Q9WVB9, (Mouse) P51141
Entrez Gene ID: (Human) 1855, (Rat) 83721, (Mouse) 13542
heart looping
outflow tract morphogenesis
regulation of transcription, DNA-templated
neurotransmitter secretion
neuromuscular junction development
Wnt signaling pathway
neural tube development
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of protein localization
protein localization to nucleus
intracellular signal transduction
non-canonical Wnt signaling pathway
receptor clustering
positive regulation of transcription from RNA polymerase II promoter
dendrite morphogenesis
synapse organization
protein stabilization
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
dendritic spine morphogenesis
presynapse assembly
postsynapse organization
regulation of postsynapse organization
positive regulation of neuron projection arborization
positive regulation of protein localization to presynapse
regulation of synaptic vesicle exocytosis
positive regulation of excitatory postsynaptic potential
regulation of neurotransmitter levels
regulation of protein phosphorylation
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
transcription from RNA polymerase II promoter
negative regulation of protein kinase activity
axonogenesis
axon guidance
positive regulation of neuron projection development
convergent extension involved in neural plate elongation
positive regulation of Wnt signaling pathway
cytoplasmic microtubule organization
negative regulation of protein binding
social behavior
protein localization to microtubule
positive regulation of transcription, DNA-templated
collateral sprouting
axon extension
convergent extension involved in organogenesis
prepulse inhibition
skeletal muscle acetylcholine-gated channel clustering
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
positive regulation of canonical Wnt signaling pathway
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