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Invitrogen
GABRG2 Polyclonal Antibody
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图: 1 / 4
GABRG2 Antibody (PA5-23698) in IHC (P)
Immunohistochemistry analysis of GABRG2 in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with GABRG2 polyclonal antibody (Product # PA5-23698) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-23698
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 198-224 amino acids from the central region of human GABRG2
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2 mg/mL
规格
800 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine and rat based on sequence homology.
靶标信息
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: GABA(A) receptor subunit gamma-2; GABA(A) receptor, gamma 2; GABAAR subunit gamma-2; GABRA2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 2; Gamma-aminobutyric acid receptor subunit gamma-2; gamma-aminobutyric acid type A receptor gamma2 subunit; unnamed protein product
基因别名: CAE2; DEE74; ECA2; EIEE74; FEB8; GABAA-R; Gabrg-2; GABRG2; gamma2; GEFSP3
UniProt ID: (Mouse) P22723
Entrez Gene ID: (Human) 2566, (Mouse) 14406
transmembrane signaling receptor activity
GABA-A receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
chloride channel activity
protein binding
benzodiazepine receptor activity
GABA-gated chloride ion channel activity
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
GABA receptor activity
ligand-gated ion channel
ion transport
chloride transport
gamma-aminobutyric acid signaling pathway
negative regulation of synaptic transmission, GABAergic
ion transmembrane transport
synaptic transmission, GABAergic
regulation of postsynaptic membrane potential
cellular response to histamine
extrasynaptic signaling via GABA
chloride transmembrane transport
inhibitory synapse assembly
transport
signal transduction
chemical synaptic transmission
post-embryonic development
adult behavior
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