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Invitrogen
IL2RG Polyclonal Antibody
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IL2RG Antibody (PA5-26461) in IHC (PFA)
Immunohistochemistry analysis of IL2RG in 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized human spleen tissue. Samples were incubated with IL2RG polyclonal antibody (Product # PA5-26461) using a dilution of 1:25 followed by Alexa Fluor 488-conjugated goat anti-rabbit IgG at a dilution of 1:400 (green). Confocal image showing membrane staining on human spleen tissue. The nuclear counter stain is D... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-26461
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 76-101 amino acids from the N-terminal region of human IL2RG
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.35 mg/mL
规格
140 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD132; CD132 antigen; common cytokine receptor gamma chain; Cytokine receptor common subunit gamma; gammaC; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL2R gamma; interleukin 2 receptor, gamma; Interleukin-2 receptor subunit gamma; nonfunctional common cytokine receptor gamma chain; p64; unnamed protein product
基因别名: CD132; CIDX; IL-2RG; IL2RG; IMD4; P64; SCIDX; SCIDX1
Entrez Gene ID: (Human) 3561
leukocyte homeostasis
immune response
signal transduction
JAK-STAT cascade
immunoglobulin mediated immune response
cytokine-mediated signaling pathway
cellular homeostasis
lymphocyte differentiation
natural killer cell activation
interleukin-15-mediated signaling pathway
interleukin-4-mediated signaling pathway
interleukin-2-mediated signaling pathway
interleukin-7-mediated signaling pathway
interleukin-9-mediated signaling pathway
positive regulation of tyrosine phosphorylation of STAT protein
negative regulation of tyrosine phosphorylation of STAT protein
negative regulation of apoptotic process
positive regulation of MAPK cascade
positive regulation of T cell differentiation
positive regulation of phagocytosis
positive regulation of leukocyte proliferation
negative regulation of Fas signaling pathway
positive regulation of leukocyte differentiation
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