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Invitrogen
GLDC Polyclonal Antibody
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图: 1 / 5
GLDC Antibody (PA5-26504) in WB
Western blot analysis was performed on whole cell extracts (30 µg lysate) of Hep G2 (Lane 1), Caco-2 (Lane 2), tissue extracts of Mouse Liver (Lane 3) and Rat Liver (Lane 4). The blot was probed with Anti-GLDC Polyclonal Antibody (Product # PA5-26504, 1:1,000 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4,000 dilution). A 112 kDa band corresponding to GLDC was observed across the cell lines and tissues tested. A non speci... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-26504
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human GLDC
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
200 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glycine cleavage system P protein; glycine cleavage system protein P; Glycine decarboxylase; glycine decarboxylase P-protein; Glycine dehydrogenase (aminomethyl-transferring); Glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase [decarboxylating], mitochondrial; nonketotic hyperglycinemia; RP11-472F14.1; unnamed protein product
基因别名: D030049L12Rik; D19Wsu57e; GCE; GCE1; GCSP; GLDC; HYGN1
UniProt ID: (Mouse) Q91W43
Entrez Gene ID: (Human) 2731, (Mouse) 104174
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