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Invitrogen
ABCD2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-26632
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 269-298 amino acids from the central region of human ABCD2
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
200 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with rat based on sequence homology.
靶标信息
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adrenoleukodystrophy related; Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; ATP-binding cassette sub-family D member 2; ATP-binding cassette, sub-family D (ALD), member 2; hALDR; unnamed protein product
基因别名: ABC39; ABCD2; ALD1; ALDL1; ALDR; ALDRP; hALDR
UniProt ID: (Mouse) Q61285
Entrez Gene ID: (Human) 225, (Mouse) 26874
long-chain fatty acid transporter activity
protein binding
ATP binding
ATPase activity
ATPase activity, coupled to transmembrane movement of substances
protein homodimerization activity
protein heterodimerization activity
acyl-CoA hydrolase activity
very long chain acyl-CoA hydrolase activity
ABC-type transporter activity
nucleotide binding
ATP-binding cassette (ABC) transporter
very long-chain fatty acid metabolic process
fatty acid biosynthetic process
fatty acid beta-oxidation
peroxisome organization
peroxisomal long-chain fatty acid import
regulation of fatty acid metabolic process
positive regulation of fatty acid beta-oxidation
very long-chain fatty acid catabolic process
myelin maintenance
positive regulation of lipid metabolic process
transmembrane transport
negative regulation of cytokine production involved in inflammatory response
negative regulation of reactive oxygen species biosynthetic process
neuron projection maintenance
positive regulation of unsaturated fatty acid biosynthetic process
transport
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