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Invitrogen
Annexin A2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-27566
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Annexin II. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.14 mg/mL
规格
14 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: A549, HCT116, HeLa, GL261, NIH-3T3, C2C12, Rat2, human ANXA2-transfected 293T.
Predicted reactivity: Mouse (98%), Rat (94%), Xenopus laevis (81%), Dog (100%), Pig (100%), Chicken (90%), Sheep (99%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 33-kDa calcimedin; 33-kDa lymphocyte Ca<2+>- binding protein; 33kDa lymphocyte Ca<2+>- binding protein; 36-kDa calelectrin; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; chromobindin 8; Chromobindin-8; Lipocortin II; p36; PAP-IV; Placental anticoagulant protein IV; Protein I
基因别名: ANX2; ANX2L4; ANXA2; AW215814; CAL1H; LPC2D
UniProt ID: (Mouse) P07356, (Rat) Q07936
Entrez Gene ID: (Mouse) 12306, (Rat) 56611
phospholipase inhibitor activity
calcium ion binding
protein binding
calcium-dependent phospholipid binding
phosphatidylinositol-4,5-bisphosphate binding
cytoskeletal protein binding
Rab GTPase binding
phospholipase A2 inhibitor activity
receptor activator activity
S100 protein binding
poly(A) RNA binding
calcium-dependent protein binding
actin filament binding
calcium-binding protein
angiogenesis
membrane raft assembly
positive regulation of protein phosphorylation
negative regulation of receptor internalization
membrane budding
body fluid secretion
collagen fibril organization
positive regulation of vesicle fusion
negative regulation of low-density lipoprotein particle receptor catabolic process
osteoclast development
fibrinolysis
negative regulation of catalytic activity
positive regulation of fibroblast proliferation
positive regulation of binding
protein heterotetramerization
cellular response to acid chemical
protein targeting to plasma membrane
negative regulation of receptor binding
positive regulation of receptor activity
regulation of fibrinolysis
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