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Invitrogen
GNAT1 Polyclonal Antibody
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GNAT1 Antibody (PA5-28336) in IHC (F)
Immunohistochemistry (Frozen) analysis of GNAT1 was performed in frozen sectioned adult mouse retina tissue using GNAT1 Polyclonal Antibody (Product # PA5-28336) at a dilution of 1:250 (Green). Red: beta Tubulin 3/ TUJ1, stained by beta Tubulin 3/ TUJ1 antibody diluted at 1:250. Blue: Fluoroshield with DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-28336
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human GNAT1. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.34 mg/mL
规格
134 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: NT2D1, IMR32, U87-MG, mouse eye.
Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (92%), Xenopus laevis (92%), Dog (99%), Chicken (96%), Bovine (98%), Guinea pig (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Guanine nucleotide-binding protein G(t) subunit alpha-1; Tr alpha; Transducin alpha-1 chain
基因别名: Gnat-1; GNAT1; GNATR; Ird1; Ird2; irdc; irdr; Tralpha; transducin
UniProt ID: (Mouse) P20612
Entrez Gene ID: (Mouse) 14685
detection of chemical stimulus involved in sensory perception of bitter taste
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
visual perception
phototransduction
phototransduction, visible light
cell proliferation
response to light intensity
rhodopsin mediated signaling pathway
eye photoreceptor cell development
response to stimulus
detection of light stimulus involved in visual perception
sensory perception of umami taste
positive regulation of cyclic-nucleotide phosphodiesterase activity
retina development in camera-type eye
cellular response to electrical stimulus
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