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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Panda, Horse, Pig, Opossum (100%); Bat, Elephant, Rabbit (94%); Turkey, Chicken (88%); Platypus, Xenopus (81%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR12 is an orphan G-protein-coupled receptor which constitutively activates the Gs protein and increases intracellular cAMP. GPR12 can also be activated by sphingosylphosphorylcholine to promote various cellular functions which include proliferation, neurite outgrowth, cell survival and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ18149; FLJ97704; G protein-coupled receptor 12; G-protein coupled receptor 12; GPCR01; MGC138349; MGC138351; R334
基因别名: Gpcr01; Gpcr12; Gpcr20; Gpcr21; GPR12
UniProt ID: (Mouse) P35412, (Rat) P30951
Entrez Gene ID: (Dog) 486034, (Bovine) 522747, (Horse) 100050970, (Pig) 100736641, (Mouse) 14738, (Rat) 80840, (Chinese hamster) 100764513