Invitrogen

MARK1 Polyclonal Antibody

Name: MARK1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-32915
Availability: InStock

查看其他5个MARK1抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

MARK1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MARK1 Antibody (PA5-32915) in IHC (P)

Immunohistochemistry analysis of MARK1 in human brain, cortex. Samples were incubated with MARK1 polyclonal antibody (Product # PA5-32915). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image MARK1 Polyclonal Antibody

产品信息

PA5-32915

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

2.5 µg/mL

产品规格

种属反应

Horse, Human, Non-human primate, Rabbit

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic 19 amino acid peptide from N-terminus of human MARK1.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

50 µg

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.1% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2550376

产品详细信息

Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Horse, Rabbit (100%); Dog, Bovine, Panda (95%); Rat, Hamster, Elephant, Platypus (89%); Mouse, Opossum, Turkey, Chicken, Lizard (84%).

For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

靶标信息

MARK1 (MARK) is a serine/threonine kinase which is involved in cytoskeletal organization and biogenesis. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. MARK1 is involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).

仅用于科研。不用于诊断过程。未经明确授权不得转售。