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Invitrogen
TCIRG1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-34419
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 19 amino acid synthetic peptide near the amino terminus of human TCIRG1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control is EL4 cell lysate.
PA5-34419 can be used with blocking peptide PEP-1461.
靶标信息
The T-cell immune regulator 1 (TCIRG1) is the a3 subunit of the vacuolar-type proton transporting ATPase (V-ATPase), a proton pump in late endosomes and lysosomes that functions in the luminal acidification of these organelles. Genetic defects in the gene encoding this protein a responsible for a severe form of autosomal recessive osteopetrosis, a condition that leads to increased bone density, decreased bone strength, and inflammation in bone tissues. TCIRG1 is also required for the normal secretion of insulin and the bacteria-killing function of macrophages.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATPase, H+ transporting, lysosomal I; ATPase, H+ transporting, lysosomal V0 protein a; OC-116 kDa; osteoclastic proton pump; Osteoclastic proton pump 116 kDa subunit; osteosclerotic; T cell immune response cDNA7 protein; T-cell immune regulator 1; T-cell immune response cDNA7 protein; T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a; T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3; TIRC7; V-ATPase 116 kDa subunit a 3; v-ATPase 116-kDa; V-ATPase a3; v-H+ATPase subunit a3; V-type proton ATPase 116 kDa subunit a; V-type proton ATPase 116 kDa subunit a 3; V-type proton ATPase 116 kDa subunit a isoform 3; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3
基因别名: ATP6a3; Atp6i; ATP6N1C; ATP6V0A3; oc; OC-116; OC116; OPTB1; Stv1; TCIRG1; TIRC7; Vph1
Entrez Gene ID: (Rat) 293650, (Mouse) 27060
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
