Invitrogen

MYCT1 Polyclonal Antibody

Name: MYCT1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-34450
Availability: InStock

查看其他4个MYCT1抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

图: 1 / 1

MYCT1 Antibody (PA5-34450) in WB

Western Blot analysis of MYCT1 in rat lung tissue lysate with MYCT1 Polyclonal Antibody (Product # PA5-34450) at (A) 1 and (B) 2 µg/mL.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

Immunogen image

Immunogen Image MYCT1 Polyclonal Antibody

产品信息

PA5-34450

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

4°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2551802

产品详细信息

A suggested positive control is rat lung tissue lysate.

PA5-34450 can be used with blocking peptide PEP-1492.

靶标信息

MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.

仅用于科研。不用于诊断过程。未经明确授权不得转售。