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Invitrogen
KANK2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-34539
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 16 amino acid peptide near the carboxy terminus of human KANK2
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control is mouse brain tissue lysate.
PA5-34539 can be used with blocking peptide PEP-1582.
靶标信息
This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ankyrin repeat domain 25; Ankyrin repeat domain-containing protein 25; KN motif and ankyrin repeat domain-containing protein 2; Matrix-remodeling-associated protein 3; SIP; SRC-1-interacting protein
基因别名: AI504612; ANKRD25; BC010245; KANK2; KIAA1518; MXRA3; RGD1563532; SIP
UniProt ID: (Rat) D3ZD05, (Mouse) Q8BX02
Entrez Gene ID: (Rat) 100361376, (Mouse) 235041
negative regulation of transcription from RNA polymerase II promoter
negative regulation of cell proliferation
negative regulation of intracellular estrogen receptor signaling pathway
negative regulation of programmed cell death
negative regulation of vitamin D receptor signaling pathway
negative regulation of G1/S transition of mitotic cell cycle
transcription, DNA-templated
regulation of transcription, DNA-templated
apoptotic process
negative regulation of stress fiber assembly
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