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Invitrogen
SLC16A13 Polyclonal Antibody
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SLC16A13 Antibody (PA5-36464) in WB
Western blot analysis of SLC16A13 in Lane 1: C6 whole cell lysate (40 µg), Lane 2: 3T3-L1 whole cell lysate (40 µg), Lane 3: MCF-7 whole cell lysate (40 µg), Lane 4: HepG2 whole cell lysate (40 µg), Lane 5: H1792 whole cell lysate (20 µg). Samples were incubated with SLC16A13 polyclonal antibody (Product # PA5-36464) at a dilution of 1:500.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-36464
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 381-426 of Human SLC16A13.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects endogenous protein at a molecular weight of 40 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MCT 13; monocarboxylate transporter; Monocarboxylate transporter 13; MOT13; solute carrier family 16 (monocarboxylic acid transporters), member 13; Solute carrier family 16 member 13; solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
基因别名: 1700007D07Rik; Mct13; Slc16a13
UniProt ID: (Mouse) Q8CF46, (Rat) Q66HE2
Entrez Gene ID: (Mouse) 69309, (Rat) 287451
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