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Invitrogen
NUP88 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-37004
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 399-444 of human NUP88
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects endogenous protein at a molecular weight of 88 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits. Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). Nup88 (nucleoporin 88 kDa) is a 741 amino acid protein that localizes to the nucleus and functions as an essential component of the nuclear pore complex. Expressed ubiquitously, Nup88 is subject to phosphorylation by ATM or ATR and is upregulated in malignant neoplasms and precancerous dysplasias, suggesting a role in tumorigenesis. The gene encoding Nup88 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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