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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This antibody detects endogenous protein at a molecular weight of 15 kDa.
Purity is >95% by SDS-PAGE.
Eppin, an epididymal protease inhibitor, belongs to the WFDC family and to the telomeric cluster. The gene encoding the protein is localized to chromosome 20q12-q13 in centromeric and telomeric clusters. It expresses three mRNAs encoding two isoforms of a cystine-rich protein that contains Kunitz-type and WAP-type (four disulfide core) protease inhibitor consensus sequences. The mouse gene lies in a cluster of putative Eppin-like genes on mouse chromosome 2. Following ejaculation, Eppin is bound to semenogelin in seminal plasma and on human spermatozoa. This complex of Eppin and Semenogelin can provide antimicrobial activity for spermatozoa. It can also provide for the preparation and survival of spermatozoa for fertility in the female reproductive tract. Eppin, which is a secreted protein, is expressed in epididymis and testis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Epididymal protease inhibitor; Eppin; EPPIN1; EPPIN2; EPPIN3; serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin); Serine protease inhibitor-like with Kunitz and WAP domains 1; serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin); WAP four-disulfide core domain protein 8
基因别名: 1700024E17Rik; Eppin; Spinlw1; Wfdc8
UniProt ID: (Rat) D4A2Z2, (Mouse) Q9DA01
Entrez Gene ID: (Rat) 685161, (Mouse) 75526