Search
Invitrogen
Phospho-EphA2/EphA5 (Tyr594) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
Phospho-EphA2/EphA5 (Tyr594) Antibody (PA5-37812) in WB
Western Blot analysis of Phospho-EphA2/EphA5 (Tyr594) was performed using extracts from JK cells (Lane 2). The lane on the left is treated with antigen-specific peptide. The membrane was probed with Phospho-EphA2/EphA5 (Tyr594) Polyclonal Antibody (Product # PA5-37812).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-37812
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide sequence around phosphorylation site of tyrosine 594 (H-T-Y(p)-E-D) derived from Human EPHA2/5.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control for Western blot is JK cells.
Target Information
These proteins belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Brain-specific kinase; CEK-7; eck-like sequence 1; EHK-1; EK7; EPH homology kinase 1; EPH-like kinase 7; Ephrin A2; Ephrin A5; Ephrin type-A receptor 2; Ephrin type-A receptor 5; EphrinA2; EphrinA5; epididymis secretory sperm binding protein; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; receptor protein-tyrosine kinase HEK7; Tyrosine-protein kinase receptor ECK; tyrosine-protein kinase receptor EHK-1; Tyrosine-protein kinase receptor MPK-5; Tyrosine-protein kinase receptor SEK-2; unnamed protein product
Gene Aliases: AI854630; ARCC2; AW125296; AW545284; BSK; CEK7; CTPA; CTPP1; CTRCT6; ECK; EHK-1; EHK1; EK7; Els1; EPHA2; EPHA5; HEK7; Myk2; Rek7; Sek-2; Sek2; TYRO4
UniProt ID: (Mouse) Q03145, (Mouse) Q60629
Entrez Gene ID: (Human) 1969, (Human) 2044, (Mouse) 13836, (Mouse) 13839
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
ephrin receptor activity
protein binding
ATP binding
growth factor binding
cadherin binding
molecular function activator activity
GPI-linked ephrin receptor activity
transmembrane-ephrin receptor activity
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
growth factor receptor binding
transmembrane signal receptor
angiogenesis
osteoblast differentiation
response to stress
transmembrane receptor protein tyrosine kinase signaling pathway
intrinsic apoptotic signaling pathway in response to DNA damage
regulation of lamellipodium assembly
cell migration
regulation of cell adhesion
keratinocyte differentiation
osteoclast differentiation
regulation of cell migration
positive regulation of cell migration
epithelial cell differentiation
mammary gland epithelial cell proliferation
negative regulation of cell adhesion mediated by integrin
regulation of blood vessel endothelial cell migration
regulation of angiogenesis
cAMP metabolic process
bone remodeling
ephrin receptor signaling pathway
animal organ development
cell motility
cell chemotaxis
branching involved in mammary gland duct morphogenesis
lens fiber cell morphogenesis
regulation of ERK1 and ERK2 cascade
response to growth factor
protein localization to plasma membrane
positive regulation of protein localization to plasma membrane
positive regulation of bicellular tight junction assembly
axon guidance
axonal fasciculation
hippocampus development
neuron development
negative regulation of insulin secretion involved in cellular response to glucose stimulus
skeletal system development
blood vessel development
vasculogenesis
protein phosphorylation
apoptotic process
cell adhesion
notochord formation
phosphorylation
peptidyl-tyrosine phosphorylation
neural tube development
cell differentiation
neuron differentiation
regulation of cell adhesion mediated by integrin
post-anal tail morphogenesis
protein kinase B signaling
axial mesoderm formation
notochord morphogenesis
negative regulation of protein kinase B signaling
notochord cell development
positive regulation of establishment of protein localization to plasma membrane
activation of GTPase activity
nervous system development
positive regulation of phosphatidylinositol 3-kinase signaling
cAMP-mediated signaling
positive regulation of CREB transcription factor activity
regulation of actin cytoskeleton organization
regulation of GTPase activity
negative regulation of synapse assembly
dendritic spine morphogenesis
regulation of insulin secretion involved in cellular response to glucose stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support