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Invitrogen
Phospho-CK2 alpha-1 (Tyr255) Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-40226
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from human Casein Kinase IIalpha around the phosphorylation site of Y255.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 0.5% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with mouse and rat based on sequence homology.
靶标信息
CSNK2A1 is a serine/threonine protein kinase that phosphorylates acidic proteins. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by CK2 alpha-1 represents the alpha subunit. While CK2 alpha-1 is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for CK2 alpha-1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: casein kinase 2 alpha; casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; Casein kinase II subunit alpha; casein kinase II, alpha 1 polypeptide; casein kinase II, alpha 1 related sequence 4; CK II alpha; CK2 catalytic subunit alpha; protein kinase CK2; protein kinase; CK2 alpha''; unnamed protein product
基因别名: CK2A1; Cka1; Cka2; CKII; Ckiia; CSNK2A1; Csnk2a1-rs4; OCNDS
UniProt ID: (Mouse) Q60737, (Rat) P19139
Entrez Gene ID: (Human) 1457, (Mouse) 12995, (Rat) 116549
double-strand break repair
protein folding
cellular response to DNA damage stimulus
signal transduction
positive regulation of cell proliferation
negative regulation of translation
peptidyl-serine phosphorylation
positive regulation of Wnt signaling pathway
positive regulation of cell growth
heterochromatin assembly
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of protein catabolic process
positive regulation of protein catabolic process
positive regulation of transcription, DNA-templated
protein stabilization
regulation of cell cycle
symbiont-mediated disruption of host cell PML body
negative regulation of signal transduction by p53 class mediator
positive regulation of aggrephagy
regulation of chromosome separation
negative regulation of double-strand break repair via homologous recombination
negative regulation of apoptotic signaling pathway
protein phosphorylation
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
protein autophosphorylation
regulation of catalytic activity
mitotic spindle checkpoint
regulation of cell growth
transcription, DNA-templated
regulation of transcription, DNA-templated
Wnt signaling pathway
regulation of cell proliferation
rhythmic process
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