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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Peptide sequence: PAPDKQGSPE LCLLSLVHLA REKSATSNKS AGIQSRRKKI LDVYANVCGV
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Anhidrotic ectodysplasin receptor 1; Downless homolog; Ectodermal dysplasia receptor; Ectodysplasin-A receptor; EDA-A1 receptor; Tumor necrosis factor receptor superfamily member EDAR
基因别名: DL; EDAR
Entrez Gene ID: (Human) 10913