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Invitrogen
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Peptide sequence: VSRNYLSQPR LTYKTVSGVN GPLVILDHVK FPRYAEIVHL TLPDGTKRSG
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
ATP6V1B2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa, isoform 2; ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B, isoform 2; ATPase, H+ transporting, V1 subunit B, isoform 2; Endomembrane proton pump 58 kDa subunit; HO57; lysosomal 56/58kDa; V-ATPase subunit B 2; V-type proton ATPase subunit B, brain isoform; Vacuolar proton pump subunit B 2
基因别名: AI194269; AI790362; ATP6B2; ATP6V1B2; HO57; R74844; Vat2; VPP3
UniProt ID: (Mouse) P62814
Entrez Gene ID: (Mouse) 11966