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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Peptide sequence: MLLEEEIPGG RRALFDSYTN LERVADYCEN NYIQSADKQR ALEETKAYTT
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Yeast: 83%; Zebrafish: 85%
ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Abelson interactor 2; Abi-2; Abl interactor 2; Abl-binding protein 3; AblBP3; Arg-binding protein 1; ArgBP1
基因别名: ABI2; ARGBPIA
Entrez Gene ID: (Human) 10152