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Invitrogen
ZDHHC16 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-48669
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 286-314 amino acids from the C-terminal region of human ZDH16.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.25 mg/mL
规格
100 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted to react with monkey and mouse based on sequence homology.
靶标信息
ZDHHC16 (zinc finger, DHHC-type containing 16), also known as APH2, is a 377 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one DHHC-type zinc finger. Existing as multiple alternatively spliced isoforms, ZDHHC16 interacts with c-Abl and catalyzes the conversion of Palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Via its association with c-Abl, ZDHHC16 may be involved in the regulation of apoptosis. The gene encoding ZDHHC16 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Abl-philin 2; DHHC-16; Palmitoyltransferase ZDHHC16; Zinc finger DHHC domain-containing protein 16
基因别名: APH2; UNQ2570/PRO6258; ZDHHC16
Entrez Gene ID: (Human) 84287
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