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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Predicted to react with rat based on sequence homology.
Transmembrane protein which mediates synaptic endocytosis and fitness-based cell culling. In response to different stimulus strengths, controls two major modes of synaptic vesicle (SV) retrieval in hippocampal neurons; Clathrin- mediated endocytosis (CME) in response to mild stimulation and activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (By similarity). In cytotoxic T-lymphoocytes (CTLs) facilitates calcium-dependent endocytosis of cytotoxic granules at the immuno synapse (By similarity). Different isoforms work as fitness fingerprints in 'loser' and 'winner' cells and thereby mediate win/lose decisions as part of the cell competition process.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Calcium channel flower domain-containing protein 1; Calcium channel flower homolog; likely ortholog of H. sapiens chromosome 9 open reading frame 7 (C9orf7)
基因别名: 5930434B04Rik; C9orf7; CACFD1; mFwe; PSEC0107; PSEC0248; UNQ3071/PRO9903
UniProt ID: (Mouse) Q8BG21
Entrez Gene ID: (Mouse) 381356