Invitrogen

MCMBP Polyclonal Antibody

Name: MCMBP Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-49723
Availability: InStock

查看其他5个MCMBP抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (3)

MCMBP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 3

MCMBP Antibody (PA5-49723) in IHC (P)

Immunohistochemical analysis of MCMBP in paraffin-embedded Human thyroid cancer tissue using (left) MCMBP Polyclonal Antibody (Product # PA5-49723) at a 1:35 dilution and (right) is treated with synthetic peptide. (Original magnification: x200).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

Immunogen image

Immunogen Image MCMBP Polyclonal Antibody

产品信息

PA5-49723

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:25-1:100

酶联免疫吸附实验 (ELISA)

1:2,000-1:5,000

产品规格

种属反应

Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide peptide corresponding to a region derived from 176-190 amino acids of human minichromosome maintenance complex binding protein

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 40% glycerol

内含物

0.05% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2635176

产品详细信息

The antibody detects endogenous level of total MCMBP protein.

靶标信息

MEK1 (Mitogen activated protein kinase kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1 activates ERK1 and ERK2 MAP kinases. Mitogen activated protein kinase kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.

仅用于科研。不用于诊断过程。未经明确授权不得转售。