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Invitrogen
MAGI2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-49843
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from internal of human MAGI2.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total MAGI2 protein.
靶标信息
Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. Florindo C.S., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004). Devroe E., J. Biol. Chem. 279:24444-24451(2004).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activin receptor interacting protein 1; Activin receptor-interacting protein 1; Acvrip1; AIP-1; Atrophin-1-interacting protein 1; Atrophin-1-interacting protein A; MAGI-2; Membrane-associated guanylate kinase inverted 2; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; S-SCAM; Synaptic-scaffolding molecule
基因别名: Acvri1; ACVRINP1; Acvrip1; AIP-1; AIP1; Arip1; KIAA0705; Magi-2; MAGI2; mKIAA0705; S-SCAM; Sscam
UniProt ID: (Rat) O88382, (Mouse) Q9WVQ1
Entrez Gene ID: (Rat) 113970, (Mouse) 50791
positive regulation of receptor internalization
glomerular filtration
signal transduction
negative regulation of cell proliferation
positive regulation of neuron projection development
phosphorylation
cytosolic transport
negative regulation of cell migration
positive regulation of phosphoprotein phosphatase activity
negative regulation of activin receptor signaling pathway
nerve growth factor signaling pathway
receptor clustering
protein heterooligomerization
negative regulation of protein kinase B signaling
SMAD protein signal transduction
mitotic cell cycle arrest
glomerular visceral epithelial cell development
cellular response to nerve growth factor stimulus
nervous system development
neuroligin clustering involved in postsynaptic membrane assembly
positive regulation of synaptic vesicle clustering
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
