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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody detects endogenous levels of total COX6C protein.
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cytochrome c oxidase polypeptide VIc; Cytochrome c oxidase polypeptide VIc-2; Cytochrome c oxidase subunit 6C; Cytochrome c oxidase subunit 6C-2; cytochrome oxidase subunit VIc; EC 1.9.3.1
基因别名: COVIc; COX-VIc; COX6C; Cox6c2
UniProt ID: (Mouse) Q9CPQ1, (Rat) P11951
Entrez Gene ID: (Mouse) 12864, (Rat) 54322