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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody detects endogenous levels of total SP100 protein.
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686E07254; FLJ00340; FLJ34579; Nuclear autoantigen Sp-100; Nuclear dot-associated Sp100 protein; SP 100; Speckled 100 kDa
基因别名: SP100
Entrez Gene ID: (Human) 6672