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Invitrogen
IFI6 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-50175
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from C-terminal of human IFI6.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total IFI6 protein.
Target Information
G1P3, also known as Interferon alpha-inducible protein 6 (IFI6) and Interferon-induced protein 6-16, is a 130 amino acid member of the IFI6 family of proteins. Localized to the mitochondria, G1P3 is a multi-pass membrane protein that is induced by IFN-α2β. G1P3 has been shown to play a major role in the apoptosis pathway. Specifically, G1P3 acts as a cell survival protein by inhibiting caspase-3 activity, which antagonizes apoptosis. G1P3 has been implicated in tumorigenesis and is the subject of therapeutic studies, as reducing G1P3-mediated antiapoptotic signals could suggest improved therapies for myeloma or other malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ifi-6-16; Interferon alpha-inducible protein 6; Interferon-induced protein 6-16
Gene Aliases: G1P3; IFI6
Entrez Gene ID: (Human) 2537
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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