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Invitrogen
ERCC6L Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-50405
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Fusion protein corresponding to residues near the C terminal of human excision repair cross-complementation group 6-like
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.2 mg/mL
规格
120 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total ERCC6L protein.
靶标信息
ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint. ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP-dependent helicase ERCC6-like; DNA excision repair protein ERCC-6-like; FLJ20105; MGC131695; PLK1-interacting checkpoint helicase; Tumor antigen BJ-HCC-15
基因别名: ERCC6L; PICH
Entrez Gene ID: (Human) 54821
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
