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Invitrogen
ABCA2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-50592
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family A (ABC1), member 2
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.8 mg/mL
Amount
80 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total ABCA2 protein.
Target Information
Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP binding cassette transporter 2; ATP-binding cassette 2; ATP-binding cassette transporter 2; ATP-binding cassette, sub-family A (ABC1), member 2; ATP-binding cassette, sub-family A, member 2; unnamed protein product
Gene Aliases: ABC2; IDPOGSA
UniProt ID: (Human) Q9BZC7
Entrez Gene ID: (Human) 20
ganglioside metabolic process
lipid metabolic process
sphingomyelin metabolic process
glycosphingolipid metabolic process
lipid transport
locomotory behavior
response to xenobiotic stimulus
regulation of steroid metabolic process
central nervous system myelin formation
regulation of intracellular cholesterol transport
negative regulation of intracellular cholesterol transport
positive regulation of low-density lipoprotein particle receptor catabolic process
cholesterol homeostasis
positive regulation of amyloid precursor protein biosynthetic process
regulation of cholesterol biosynthetic process
negative regulation of steroid metabolic process
sphingosine biosynthetic process
response to steroid hormone
positive regulation of protein metabolic process
transmembrane transport
response to cholesterol
negative regulation of phospholipid biosynthetic process
negative regulation of sphingolipid biosynthetic process
cellular sphingolipid homeostasis
negative regulation of cholesterol efflux
ceramide translocation
transport across blood-brain barrier
regulation of post-translational protein modification
positive regulation of beta-amyloid formation
positive regulation of amyloid precursor protein catabolic process
regulation of protein localization to cell periphery
negative regulation of receptor-mediated endocytosis involved in cholesterol transport
regulation of protein localization to cell surface
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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