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Invitrogen
LLGL1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-50698
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human lethal giant larvae homolog 1
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.4 mg/mL
Amount
140 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total LLGL1 protein.
Target Information
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hugl; Hugl protein; human homolog to the D-lgl gene protein; lethal giant larvae homolog 1, scribble cell polarity complex component; LLGL; LLGL1, scribble cell polarity complex component
Gene Aliases: DLG4; HUGL; HUGL-1; HUGL1; Lgl1; LLGL; Mgl1
UniProt ID: (Human) Q15334
Entrez Gene ID: (Human) 3996
Golgi to plasma membrane transport
axonogenesis
regulation of Notch signaling pathway
cortical actin cytoskeleton organization
regulation of establishment or maintenance of cell polarity
establishment or maintenance of epithelial cell apical/basal polarity
establishment of spindle orientation
protein-containing complex assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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