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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody detects endogenous levels of total RASA2 protein.
The Ras-related low molecular mass GTPases participate in signal transduction involving a variety of cellular functions, including cell-cycle progression, cellular differentiation, cytoskeletal organization, protein transport and secretion. The Ras-GTPase-activating protein (RASGAP) forms a complex with a second protein, p190, in growth factor stimulated and tyrosinekinase transformed cells. The RASGAP p190 complex may serve to couple Ras- and Rho-mediated signaling pathways. RASGAP forms an abundant SH2-mediated complex with p190 RhoGAP in cells expressing activated tyrosine kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CM-AVM; CMAVM; DKFZp434N071; GAP; GAP1m; GTPase-activating protein 1m; p120GAP; p120RASGAP; PKWS; Ras GTPase-activating protein 2; RASA
Gene Aliases: GAP1M; RASA2; RASGAP
Entrez Gene ID: (Human) 5922
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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