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Invitrogen
TCEB1 Polyclonal Antibody
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TCEB1 Antibody (PA5-50802) in IHC (P)
Immunohistochemical analysis of TCEB1 in paraffin-embedded The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using (left) TCEB1 Polyclonal Antibody (Product # PA5-50802) at a 1:40 dilution and (right) is treated with fusion protein. (Original magnification: x200).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-50802
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Full length fusion protein of Human TCEB1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.2 mg/mL
规格
220 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total TCEB1 protein.
靶标信息
TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EloC; elongation factor SIII p15 subunit; Elongin 15 kDa subunit; elongin C; Elongin-C; RNA polymerase II transcription factor SIII subunit C; SIII p15; Stromal membrane-associated protein SMAP1B homolog; Transcription elongation factor B polypeptide 1
基因别名: 2610043E24Rik; 2610301I15Rik; AA407206; AI987979; AW049146; ELOC; TCEB1
UniProt ID: (Rat) P83941, (Mouse) P83940
Entrez Gene ID: (Rat) 64525, (Mouse) 67923
transcription, DNA-templated
ubiquitin-dependent protein catabolic process
protein ubiquitination
positive regulation of transcription elongation from RNA polymerase II promoter
regulation of transcription, DNA-templated
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
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