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Invitrogen
DPYD Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-51090
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from the Internal region of human DPYD.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 0.5% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
DPYD Polyclonal Antibody detects endogenous levels of DPYD protein.
靶标信息
Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DHPDHase; Dihydropyrimidine dehydrogenase [NADP(+)]; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase; DPD
基因别名: AI315208; DPD; DPYD; E330028L06Rik
UniProt ID: (Rat) O89000, (Mouse) Q8CHR6
Entrez Gene ID: (Rat) 81656, (Mouse) 99586
uracil binding
dihydroorotate dehydrogenase activity
dihydropyrimidine dehydrogenase (NADP+) activity
protein homodimerization activity
metal ion binding
NADP binding
iron-sulfur cluster binding
4 iron, 4 sulfur cluster binding
nucleotide binding
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
purine nucleobase catabolic process
pyrimidine nucleobase catabolic process
thymine catabolic process
uracil catabolic process
thymidine catabolic process
UMP biosynthetic process
response to nutrient
circadian rhythm
beta-alanine biosynthetic process
uracil metabolic process
response to drug
response to glucocorticoid
oxidation-reduction process
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
