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Invitrogen
CCBL1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-51313
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length fusion protein of human CCBL1
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.2 mg/mL
Amount
120 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total CCBL1 protein.
Target Information
Kynurenine aminotransferases KAT I, KAT II, and KAT III belong to the class-I pyridoxal-phosphate-dependent aminotransferase family. KAT I is a cytoplasmic protein involved in glutamine catabolism. KAT I functions in the catalysis of the transamination of L-kinurenine to form kynurenic acid, a neuroprotective and anticonvulsant metabolite of tryptophan. Kynurenic acid is involved in synaptic transmission and has been implicated in a number of neurological disorders including schizophrenia and Huntington's disease. KAT I also functions in the metabolism of cysteine conjugates in some halogenated alkenes and alkanes to form reactive metabolites. KAT I has three isoforms. Isoform 1is the full length protein, isoform 2 lacks amino acids 68-117 and isoform 3 lacks amino acids 251-422. Based on sequence similarity, KAT I is thought to function as a homodimer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cysteine conjugate-beta lyase 1; Cysteine-S-conjugate beta-lyase; Glutamine transaminase K; Glutamine--phenylpyruvate transaminase; GTK; KATI; Kynurenine aminotransferase 1; Kynurenine aminotransferase I; kynurenine aminotransferase/glutamine transaminase K; Kynurenine--oxoglutarate transaminase 1; kynurenine--oxoglutarate transaminase 1, mitochondrial; Kynurenine--oxoglutarate transaminase I
Gene Aliases: CCBL1; Gtk; Kat; Kat1; KatI; KYAT1
UniProt ID: (Rat) Q08415
Entrez Gene ID: (Rat) 311844
kynurenine-oxoglutarate transaminase activity
lyase activity
pyridoxal phosphate binding
protein homodimerization activity
L-phenylalanine:pyruvate aminotransferase activity
glutamine-phenylpyruvate transaminase activity
cysteine-S-conjugate beta-lyase activity
L-glutamine:pyruvate aminotransferase activity
transaminase
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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