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Phospho-FGFR2 (Ser782) Polyclonal Antibody detects endogenous levels of FGFR2 only when phosphorylated at Ser782.
FGFR2 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR family members differ from one another in their ligand affinities and tissue distribution. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD332; FGF Receptor; FGF Receptor 2; FGF-10; FGFR; FGFR-2; Fibroblast growth factor receptor 2; K-sam; Keratinocyte growth factor receptor; KGFR; Soluble KGFR
基因别名: AU043015; AW556123; BEK; Ect1; Fgfr-2; Fgfr-7; FGFR2; Fgfr7; KGFR; KGFRTr; KSAM; svs
UniProt ID: (Mouse) P21803
Entrez Gene ID: (Mouse) 14183