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Invitrogen
SLC27A1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-67913
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from human SLC27A1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted to react with Mouse and Rat samples.
靶标信息
SLC27A1 is a protein coding gene. Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ACSVL5FATP-1; Arachidonate--CoA ligase; EC 6.2.1; FATP-1; Fatty acid transport protein; Fatty acid transport protein 1; FLJ00336; Long-chain fatty acid transport protein 1; Long-chain-fatty-acid--CoA ligase; MGC71751; Solute carrier family 27 member 1; solute carrier family 27, member 1; Very long-chain acyl-CoA synthetase; Vlc27a1
基因别名: ACSVL5; FATP; FATP1; SLC27A1
UniProt ID: (Mouse) Q60714
Entrez Gene ID: (Rat) 94172, (Mouse) 26457
nucleotide binding
long-chain fatty acid-CoA ligase activity
protein binding
fatty acid transporter activity
very long-chain fatty acid-CoA ligase activity
protein homodimerization activity
catalytic activity
acyl-CoA ligase activity
succinate-CoA ligase activity
3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity
fatty acid ligase activity
ligase activity
3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity
2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity
benzoyl acetate-CoA ligase activity
2,4-dichlorobenzoate-CoA ligase activity
pivalate-CoA ligase activity
cyclopropanecarboxylate-CoA ligase activity
adipate-CoA ligase activity
citronellyl-CoA ligase activity
mentha-1,3-dione-CoA ligase activity
thiophene-2-carboxylate-CoA ligase activity
2,4,4-trimethylpentanoate-CoA ligase activity
cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
branched-chain acyl-CoA synthetase (ADP-forming) activity
aryl-CoA synthetase (ADP-forming) activity
3-hydroxypropionyl-CoA synthetase activity
perillic acid:CoA ligase (ADP-forming) activity
perillic acid:CoA ligase (AMP-forming) activity
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity
pristanate-CoA ligase activity
malonyl-CoA synthetase activity
transporter
secondary carrier transporter
medium-chain fatty acid transport
long-chain fatty acid metabolic process
phosphatidylethanolamine biosynthetic process
phosphatidic acid biosynthetic process
phosphatidylglycerol biosynthetic process
phosphatidylcholine biosynthetic process
phosphatidylserine biosynthetic process
phosphatidylinositol biosynthetic process
biological_process
response to cold
fatty acid transport
long-chain fatty acid transport
positive regulation of heat generation
cardiolipin biosynthetic process
response to insulin
adiponectin-activated signaling pathway
negative regulation of phospholipid biosynthetic process
positive regulation of protein serine/threonine kinase activity
lipid metabolic process
fatty acid metabolic process
transport
lipid transport
metabolic process
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