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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 85%; Rat: 93%
This gene encodes a uridine 5' -monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5' -monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5' -monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ACCELERATED CELL DEATH 2; Adrenocortical dysplasia protein homolog; AP22.36; AP22_36; ARABIDOPSIS THALIANA RED CHLOROPHYLL CATABOLITE REDUCTASE; AT4G37000; ATRCCR; POT1 and TIN2-interacting protein; RCCR; RED CHLOROPHYLL CATABOLITE REDUCTASE; TPP 1; TPP I; TPPI
基因别名: ACD; PIP1; PTOP; TINT1; TPP1
Entrez Gene ID: (Human) 65057