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Invitrogen
EIF2B4 Polyclonal Antibody
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FIGURE: 1 / 3
EIF2B4 Antibody (PA5-71496) in IHC (P)
Immunohistochemistry analysis of EIF2B4 in formalin fixed and paraffin embedded human skeletal muscle. Samples were incubated with EIF2B4 polyclonal antibody (Product # PA5-71496) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-71496
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 146-175 amino acids from the Central region of human EIF2B4
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.45 mg/mL
Amount
180 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp586J0119; eIF-2B GDP-GTP exchange factor subunit delta; eIF2B GDP-GTP exchange factor subunit delta; translation initiation factor eIF-2B subunit delta; Translation initiation factor eIF2B subunit delta
Gene Aliases: Eif2b; EIF2B4; EIF2BD; Jgr1a
UniProt ID: (Mouse) Q61749
Entrez Gene ID: (Mouse) 13667
ovarian follicle development
translation
translational initiation
regulation of translation
response to heat
response to glucose
oligodendrocyte development
negative regulation of translational initiation in response to stress
myelination
response to peptide hormone
positive regulation of GTPase activity
cellular metabolic process
negative regulation of translational initiation
cellular response to stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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