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Invitrogen
C/EBP delta/epsilon Polyclonal Antibody
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C/EBP delta/epsilon Antibody (PA5-75232) in IHC (P)
Immunohistochemistry analysis of C/EBP delta/epsilon in paraffin-embedded human breast carcinoma tissue (cytoplasmic and nucleus staining) and negative control (right, with PBS only). Samples were incubated with C/EBP delta/epsilon polyclonal antibody (Product # PA5-75232) at a dilution of 1:50, followed by goat Anti-Rabbit IgG-biotin and avidin peroxidase.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-75232
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 200-250 of Human C/EBP-delta.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
C/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP α uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic α helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP α appears to function exclusively in terminally-differentiated, growth-arrested cells. Additional family members include C/EBP β, C/EBP γ, C/EBP δ and C/EBP ε, all of which exhibit similar DNA-binding specificities and affinities to C/EBP α. Furthermore, C/EBP β and C/EBP δ readily form heterodimers both with each other as well as with C/EBP α.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C EBP; C/EBP delta; C/EBP epsilon; C/EBP-related protein 1; C/EBP-related protein 3; C/EBPdelta; C/EBPepsilon; CCAAT/enhancer binding protein , epsilon; CCAAT/enhancer binding protein epsilon; CCAAT/enhancer-binding protein delta; CCAAT/enhancer-binding protein epsilon; NF-IL6-beta; Nuclear factor NF-IL6-beta; Transcription factor CELF
基因别名: C/EBPd; C/EBPe; C/EPBe; CEBPD; CEBPE; CELF; CRP1; Crp3; Gm294
UniProt ID: (Mouse) Q00322, (Rat) Q03484, (Rat) P56261, (Mouse) Q6PZD9
Entrez Gene ID: (Mouse) 12609, (Rat) 25695, (Rat) 25410, (Mouse) 110794
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
basic leucine zipper transcription factor
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
fat cell differentiation
positive regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
inner ear development
phagocytosis
positive regulation of gene expression
myeloid cell differentiation
macrophage differentiation
cytokine biosynthetic process
defense response to bacterium
cellular response to lipopolysaccharide
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