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Invitrogen
hnRNP C1/C2 Polyclonal Antibody
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hnRNP C1/C2 Antibody (PA5-75278) in IHC (P)
Immunohistochemistry analysis of hnRNP C1/C2 in paraffin-embedded human colon carcinoma tissue. Samples were incubated with hnRNP C1/C2 polyclonal antibody (Product # PA5-75278) using a dilution of 1:50 (showing nucleus staining). Secondary antibody: Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase. Negative control (the right) using PBS instead of primary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-75278
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 241-290 of Human hnRNP C1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: heterogeneous nuclear ribonucleoprotein C; heterogeneous nuclear ribonucleoprotein C (C1/C2); Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C protein C-terminal fragment (158 AA); hnRNP C1/C2; hnRNP core protein C
基因别名: hnRNP C; HNRNPC; HNRPC
Entrez Gene ID: (Rat) 290046
nucleotide binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
nucleic acid binding
RNA binding
mRNA binding
mRNA 3'-UTR binding
poly(U) RNA binding
nucleosomal DNA binding
identical protein binding
poly(A) RNA binding
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
