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Invitrogen
Serum Amyloid P Polyclonal Antibody
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Serum Amyloid P Antibody (PA5-76026) in IHC (P)
Immunohistochemistry analysis of Serum Amyloid P in paraffin-embedded mouse liver. Samples were incubated with Serum Amyloid P polyclonal antibody (Product # PA5-76026) using a dilution of 1:100. Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-76026
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human Serum Amyloid P.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 9.5S alpha-1-glycoprotein; APCS amyloid P-component serum protein; MGC88159; Pentaxin related; Pentraxin 2; PTX 2; SAMP; SAP; Serum amyloid P-component
基因别名: APCS; PTX2; Sap
UniProt ID: (Mouse) P12246, (Rat) P23680
Entrez Gene ID: (Mouse) 20219, (Rat) 29339
protein complex assembly
negative regulation by host of viral exo-alpha-sialidase activity
negative regulation by host of viral glycoprotein metabolic process
innate immune response
negative regulation of monocyte differentiation
negative regulation of viral entry into host cell
negative regulation of viral process
negative regulation of exo-alpha-sialidase activity
negative regulation of glycoprotein metabolic process
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