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Invitrogen
PLCB1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-76089
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human PLCB1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1; phosphoinositide phospholipase C; Phosphoinositide phospholipase C-beta-1; phosphoinositide-specific phospholipase c; Phospholipase C-beta-1; phospholipase C-beta-1a; Phospholipase C-beta1; Phospholipase C-I; PLC-154; PLC-beta-1; PLC-I
基因别名: 3110043I21Rik; AI132408; KIAA0581; mKIAA0581; Phosphb; PLC'1; Plcb; PLCB1; PLCbeta1; RATPHOSPHB
UniProt ID: (Rat) P10687, (Mouse) Q9Z1B3
Entrez Gene ID: (Rat) 24654, (Mouse) 18795
phosphatidylinositol phospholipase C activity
signal transducer activity
GTPase activator activity
calcium ion binding
protein binding
calmodulin binding
lamin binding
phosphatidylinositol-4,5-bisphosphate binding
enzyme binding
protein homodimerization activity
phosphoric diester hydrolase activity
hydrolase activity
phospholipase
G2/M transition of mitotic cell cycle
G-protein coupled acetylcholine receptor signaling pathway
glutamate receptor signaling pathway
learning
memory
regulation of G-protein coupled receptor protein signaling pathway
response to organonitrogen compound
lipid catabolic process
cerebral cortex development
positive regulation of interleukin-12 production
response to monosaccharide
intracellular signal transduction
interleukin-12-mediated signaling pathway
interleukin-15-mediated signaling pathway
positive regulation of embryonic development
response to peptide hormone
positive regulation of GTPase activity
fat cell differentiation
positive regulation of myoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of JNK cascade
phosphatidylinositol metabolic process
insulin-like growth factor receptor signaling pathway
positive regulation of developmental growth
activation of meiosis involved in egg activation
interleukin-1-mediated signaling pathway
regulation of fertilization
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of acrosome reaction
negative regulation of monocyte extravasation
positive regulation of CD24 biosynthetic process
oocyte maturation
mRNA processing
lipid metabolic process
cell adhesion
signal transduction
brain development
insulin receptor signaling pathway
erythrocyte differentiation
macrophage differentiation
positive regulation of sodium:proton antiporter activity
regulation of cell cycle
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