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Invitrogen
RAPGEF3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-76094
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human RAPGEF3.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Gene ontology (GO) annotation includes small GTPase mediated signal transduction. Target protein binds cAMP and activates the Ras superfamily guanine nucleotide binding protein (Rap1A)in a PKA-independent manner.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cAMP-GEFI; cAMP-regulated guanine nucleotide exchange factor I; EPAC 1; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; MGC21410; Rap guanine nucleotide exchange factor 3; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP
基因别名: 2310016P22Rik; 9330170P05Rik; CGEF1; EPAC; EPAC1; RAPGEF3
UniProt ID: (Mouse) Q8VCC8
Entrez Gene ID: (Mouse) 223864
angiogenesis
regulation of protein phosphorylation
positive regulation of protein phosphorylation
small GTPase mediated signal transduction
positive regulation of smooth muscle cell migration
Rap protein signal transduction
positive regulation of ATPase activity
negative regulation of collagen biosynthetic process
positive regulation of peptidyl-serine phosphorylation
negative regulation of syncytium formation by plasma membrane fusion
intracellular signal transduction
positive regulation of GTPase activity
positive regulation of angiogenesis
positive regulation of cell size
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein export from nucleus
positive regulation of binding
positive regulation of stress fiber assembly
positive regulation of calcium ion transport
positive regulation of syncytium formation by plasma membrane fusion
negative regulation of cell death
establishment of endothelial barrier
cellular response to cAMP
positive regulation of protein acetylation
regulation of actin cytoskeleton reorganization
positive regulation of actin cytoskeleton reorganization
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