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Invitrogen
CHIA Polyclonal Antibody
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CHIA Antibody (PA5-76096) in IHC (P)
Immunohistochemistry analysis of CHIA in paraffin-embedded human esophageal cancer. Samples were incubated with CHIA polyclonal antibody (Product # PA5-76096) using a dilution of 1:100. Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-76096
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human CHIA.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acidic chitinase; Acidic mammalian chitinase; AMCase; eosinophil chemotactic cytokine; Lung-specific protein TSA1902; small acid mammalian chitinase; YNL
基因别名: 2200003E03Rik; AMCase; CHIA; Chia1; YNL
UniProt ID: (Rat) Q6RY07, (Mouse) Q91XA9
Entrez Gene ID: (Rat) 113901, (Mouse) 81600
polysaccharide catabolic process
production of molecular mediator involved in inflammatory response
carbohydrate metabolic process
chitin catabolic process
apoptotic process
immune response
positive regulation of chemokine secretion
immune system process
chitin metabolic process
inflammatory response
metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
