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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ZDHHC16 (zinc finger, DHHC-type containing 16), also known as APH2, is a 377 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one DHHC-type zinc finger. Existing as multiple alternatively spliced isoforms, ZDHHC16 interacts with c-Abl and catalyzes the conversion of Palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Via its association with c-Abl, ZDHHC16 may be involved in the regulation of apoptosis. The gene encoding ZDHHC16 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Abl-philin 2; ablphilin-2; DHHC-16; membrane-associated DHHC16 zinc finger protein; Palmitoyltransferase ZDHHC16; probable palmitoyltransferase ZDHHC16; Zinc finger DHHC domain-containing protein 16; zinc finger, DHHC domain containing 16
基因别名: 1500015N03Rik; APH2; UNQ2570/PRO6258; ZDHHC16
UniProt ID: (Mouse) Q9ESG8
Entrez Gene ID: (Rat) 654495, (Mouse) 74168