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Invitrogen
COX10 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-77244
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human COX10.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Defects in COX10 are a cause of mitochondrial complex IV deficiency (MT-C4D); also known as cytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patients manifest Leigh syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase; Heme O synthase; Protoheme IX farnesyltransferase, mitochondrial
基因别名: 2410004F01Rik; AU042636; COX10
UniProt ID: (Mouse) Q8CFY5
Entrez Gene ID: (Mouse) 70383
cytochrome-c oxidase activity
farnesyltranstransferase activity
prenyltransferase activity
protein geranylgeranyltransferase activity
protein prenyltransferase activity
4-hydroxybenzoate octaprenyltransferase activity
protoheme IX farnesyltransferase activity
transferase activity
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity
cadaverine aminopropyltransferase activity
agmatine aminopropyltransferase activity
1,4-dihydroxy-2-naphthoate octaprenyltransferase activity
trans-pentaprenyltranstransferase activity
ATP dimethylallyltransferase activity
ADP dimethylallyltransferase activity
acyltransferase
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
