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Invitrogen
BAG1 Polyclonal Antibody
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FIGURE: 1 / 6
BAG1 Antibody (PA5-78851) in IHC (P)
Immunohistochemistry (Paraffin) analysis of BAG1 in paraffin-embedded section of human colorectal adenocarcinoma tissue using BAG1 Polyclonal Antibody (Product # PA5-78851). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilution... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-78851
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Bag1 (323-345aa DTVEQNICQETERLQSTNFALAE).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human Jurkat whole cell, human MCF-7 whole cell, human 293T whole cell. IHC: human breast cancer tissue, human colorectal adenocarcinoma tissue, human tonsil tissue, mouse colon tissue, rat colon tissue.
Target Information
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BAG-1L; BAG-1L; long form of BAG-1; contains nuclear localization signal; Bcl-2 associating athanogene-1 protein; bcl-2-associated athanogene 1; Bcl-2-binding protein; BCL2 associated athanogene 1; BCL2-associated athanogene; glucocortoid receptor-associated protein RAP46; receptor-associated protein, 46-KD; RP11-326F20.2; unnamed protein product
Gene Aliases: BAG-1; HAP; RAP46
UniProt ID: (Human) Q99933, (Mouse) Q60739, (Rat) B0K019
Entrez Gene ID: (Human) 573, (Mouse) 12017, (Rat) 297994
protein folding
cell surface receptor signaling pathway
positive regulation of smooth muscle cell apoptotic process
negative regulation of apoptotic process
protein stabilization
negative regulation of protein phosphorylation
positive regulation of Schwann cell differentiation
neuron differentiation
positive regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
protein localization to mitochondrion
negative regulation of motor neuron apoptotic process
response to xenobiotic stimulus
response to nicotine
response to benzene
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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